Sedivet Injection is used as a sedative and analgesic to facilitate handling, or during clinical examinations, clinical procedures, and minor surgical procedures in adult horses. the Injection is also indicated as a preanesthetic prior to the induction of general anesthesia in adult horses. it contains romifidine hydrochloride. Sedivet 1% Injection is recommended for IV administration. Romifidine hydrochloride.
Warnings and cautions for Sedivet 1% Injection
Direction and dosage information for Sedivet 1% Injection
Sedivet 1% Injection
This treatment applies to the following species:
Company: Boehringer Ingelheim
NADA 141-229, Approved by FDA
Sedative and analgesic drug for intravenous use in horses only
Sedivet 1% Injection Caution
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Sedivet 1.0% Injection (romifidine hydrochloride) is an α2-adrenoceptor agonist with sedative and analgesic properties. The chemical name is 2-bromo-6-fluoro-2-imidazolidinyliden-benzamine-monohydrochloride. It is a crystalline, white, odorless, water soluble substance with a molecular formula of C9H9BrFN3•HCl, and a molecular weight of 294.56. Each mL contains 10 mg romifidine hydrochloride, 6.5 mg sodium chloride, 2 mg chlorocresol, and water for injection.
the Injection Indications
Injection is indicated for use as a sedative and analgesic to facilitate handling, clinical examinations, clinical procedures, and minor surgical procedures in adult horses. Sedivet 1.0% Injection is also indicated as a preanesthetic prior to the induction of general anesthesia in adult horses.
Dosage and Administration
Sedation and Analgesia Dose: Administer slowly as a single IV injection using a dosage range of 40 – 120 µg/kg (0.4 – 1.2 mL/100 kg body weight) depending on the depth and duration of sedation that is required. The onset of action occurs in 30 seconds to 5 minutes, and gradually subsides during the next 2 to 4 hours. Degree of sedation and analgesia is dose- and time-dependent; therefore, more profound analgesia will occur with larger doses, as well as closer to the time of injection.
Note: The animal should be allowed to rest quietly for several minutes prior to and following injection.